VIDEO: Why you can’t compare Covid-19 vaccines – by Vox

  Why you can’t compare Covid-19 vaccines– by Vox

What a vaccine’s “efficacy rate” actually means.

In the US, the first two available Covid-19 vaccines were the ones from Pfizer/BioNTech and Moderna. Both vaccines have very high “efficacy rates,” of around 95%. But the third vaccine introduced in the US, from Johnson & Johnson, has a considerably lower efficacy rate: just 66%.       

Look at those numbers next to each other, and it’s natural to conclude that one of them is considerably worse. Why settle for 66% when you can have 95%? But that isn’t the right way to understand a vaccine’s efficacy rate, or even to understand what a vaccine does. And public health experts say that if you really want to know which vaccine is the best one, efficacy isn’t actually the most important number at all.

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Further reading from Vox: Why comparing Covid-19 vaccine efficacy numbers can be misleading: https://www.vox.com/22311625/covid-19… The vaccine metric that matters more than efficacy: https://www.vox.com/22273502/covid-va… The limits of what vaccine efficacy numbers can tell us: https://www.vox.com/21575420/oxford-m…

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Comments

  • brandli62  On 03/30/2021 at 9:22 am

    Why you can’t compare Covid-19 vaccines– by Vox

    This is an excellent explanatory video illustrating why you cannot directly compare clinical test data of the different covid-19 vaccines. In order to do so, you would have to test all covid-19 vaccines in parallel in the same study. This has not been done today. However, the clinical trials have demonstrated that all currently approved (by FDA or EMA) covid-19 vaccines are 100% effective. Hence, if you have a chance to be vaccinated against covid-19, take the opportunity to do so!

  • wally n  On 03/30/2021 at 11:07 am

    Every time I try to get away…they pull me back. Any truth in this doc?

    AstraZeneca has renamed its Covid-19 vaccine, a move that coincides with the company’s struggle to reassure the public that its drug is safe, following numerous reports of potential adverse effects.

    The British-Swedish pharmaceutical has rebranded its jab, which previously went by the simple ‘AstraZeneca Covid-19 Vaccine’, to ‘Vaxzevria’. In a press release, the company said that the name change does not involve any alterations to the actual drug. Medical workers should be made aware of the rebrand though, the firm said, because the labeling and packaging can look different.

  • brandli62  On 03/30/2021 at 3:30 pm

    30 million Brits were vaccinated with the Oxford/AZ covid-19 vaccine. Side-effects are minimal. All my relatives in Guyana were recently vaccinated with the same vaccine. They are all doing fine.

  • wally n  On 03/30/2021 at 4:01 pm

    Good to know thanks.

  • Clyde Duncan  On 04/01/2021 at 4:56 am

    The EU’s medical regulator has said that there is no evidence to support decisions by several countries such as Germany and France to stop using the AstraZeneca jab on younger adults over concerns about rare blood clots.

    At least 44 of the 9.2 million people who have received the jab across Europe suffered blood clots on the brain, with 14 of these patients dying.

    Source: The Times UK

  • brandli62  On 04/01/2021 at 5:17 am

    The blood clothing condition observed after vaccination with the AZ vaccine is very rare and it appears that it is treatable by as long as it is recognised early be the medical staff:

    Treatable condition
    [Dr.] Greinacher agrees on the need for more data. But he says it’s crucial to alert doctors to the potential complication. When recognized in time, HIT [heparin induced thrombocytopenia] can be treated with immunoglobulins—nonspecific antibodies from blood donors—that help put the brakes on platelet activation. Nonheparin blood thinners can help dissolve the clots. VIPIT [vaccine-induced prothrombotic immune thrombocytopenia] should be treated in a similar way, he says. In at least one case, Greinacher says, a doctor sought the group’s advice and the patient recovered.

    Reference:
    A rare clotting disorder may cloud the world’s hopes for AstraZeneca’s COVID-19 vaccine

    https://www.sciencemag.org/news/2021/03/rare-clotting-disorder-may-cloud-worlds-hopes-astrazenecas-covid-19-vaccine

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